Quadro 4000 vs Radeon Pro 5300M

In this comparison between Quadro 4000 and Radeon Pro 5300M you will find out which graphics card performs better in today's games. Bear in mind that third-party versions may have more efficient cooling and higher clock speeds. This will increase cards' performance, though not by much. In addition to raw power you should also take into account the dimensions. Thicker models simply will not fit into a small mini-ITX case. The resolution of your monitor also affects the choice, since 4K gameplay requires a more powerful GPU. And don't overspend on the graphics card. Other parts of your build may also need to be upgraded, save some money for the CPU or power supply. For some people Quadro 4000 will be the best choice, for others Radeon Pro 5300M will be their preference. Study the comparison tables below and make your choice.

Radeon Pro 5300M is a Laptop Graphics Card

Note: Radeon Pro 5300M is only used in laptop graphics. It has lower GPU clock speed compared to the desktop variant, which results in lower power consumption, but also 10-30% lower gaming performance. Check available laptop models with Radeon Pro 5300M here:

Main Specs

  Quadro 4000 Radeon Pro 5300M
Power consumption (TDP) 142 Watt 85 Watt
Interface PCIe 2.0 x16 PCIe 4.0 x8
Supplementary power connectors 1x 6-pin None
Memory type GDDR5 GDDR6
Maximum RAM amount 2 GB 4 GB
Display Connectors 1x DVI, 2x DisplayPort No outputs
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  • Quadro 4000 has 67% more power consumption, than Radeon Pro 5300M.
  • Quadro 4000 is connected by PCIe 2.0 x16, and Radeon Pro 5300M uses PCIe 4.0 x8 interface.
  • Radeon Pro 5300M has 2 GB more memory, than Quadro 4000.
  • Quadro 4000 is used in Desktops, and Radeon Pro 5300M - in Mobile workstations.
  • Quadro 4000 is build with Fermi architecture, and Radeon Pro 5300M - with Navi / RDNA.
  • Quadro 4000 is manufactured by 40 nm process technology, and Radeon Pro 5300M - by 7 nm process technology.
  • Memory clock speed of Radeon Pro 5300M is 9192 MHz higher, than Quadro 4000.

Game benchmarks

high / 1080p 6−7 35−40
ultra / 1080p 4−5 21−24
QHD / 1440p 0−1 16−18
4K / 2160p 10−11
low / 720p 16−18 60−65
medium / 1080p 8−9 40−45
The average gaming FPS of Radeon Pro 5300M in Assassin's Creed Odyssey is 355% more, than Quadro 4000.

Full Specs

  Quadro 4000 Radeon Pro 5300M
Architecture Fermi Navi / RDNA
Code name GF100 Navi 14
Type Workstation Mobile workstation
Release date 2 November 2010 13 November 2019
Pipelines 256 1280
Core clock speed 475 MHz
Boost Clock 1250 MHz
Transistor count 3,100 million 6,400 million
Manufacturing process technology 40 nm 7 nm
Texture fill rate 15.20 100.0
Floating-point performance 486.4 gflops
Length 241 mm
Memory bus width 256 Bit 128 Bit
Memory clock speed 2808 MHz 12000 MHz
Memory bandwidth 89.86 GB/s 192.0 GB/s
Shared memory -
DirectX 12 (11_0) 12 (12_1)
Shader Model 5.1 6.5
OpenGL 4.6 4.6
OpenCL 1.1 2.0
Vulkan N/A 1.2.131
CUDA 2.0
Bitcoin / BTC (SHA256) 44 Mh/s
Laptop size medium sized
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