Quadro 4000 vs Radeon R9 A375

If you are going to buy a new graphics card and are choosing between Quadro 4000 and Radeon R9 A375, there are a couple of things to consider. Cards with more VRAM in general perform better and allow you to play on higher graphics settings. Size also makes a difference. A model with a large heatsink can occupy up to three expansion slots on a motherboard. Be sure you have enough room in your PC case. When comparing GPUs with different architectures, more processing cores and even higher TFLOPS will not always translate to better performance. To help you decide which GPU you need, we have measured frame rates in a number of popular games. For more on how the Quadro 4000 stacks up against Radeon R9 A375, check out specs charts below.

Main Specs

  Quadro 4000 Radeon R9 A375
Power consumption (TDP) 142 Watt
Interface PCIe 2.0 x16 PCIe 3.0 x16
Supplementary power connectors 1x 6-pin
Memory type GDDR5 GDDR5
Maximum RAM amount 2 GB 2 GB
Display Connectors 1x DVI, 2x DisplayPort No outputs
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  • Quadro 4000 is connected by PCIe 2.0 x16, and Radeon R9 A375 uses PCIe 3.0 x16 interface.
  • Quadro 4000 and Radeon R9 A375 have maximum RAM of 2 GB.
  • Both cards are used in Desktops.
  • Quadro 4000 is build with Fermi architecture, and Radeon R9 A375 - with GCN 1.0.
  • Core clock speed of Radeon R9 A375 is 425 MHz higher, than Quadro 4000.
  • Quadro 4000 is manufactured by 40 nm process technology, and Radeon R9 A375 - by 28 nm process technology.
  • Memory clock speed of Quadro 4000 is 2804 MHz higher, than Radeon R9 A375.

Game benchmarks

high / 1080p 6−7 2−3
ultra / 1080p 4−5 1−2
QHD / 1440p 0−1 0−1
low / 720p 16−18 12−14
medium / 1080p 8−9 4−5
The average gaming FPS of Quadro 4000 in Assassin's Creed Odyssey is 80% more, than Radeon R9 A375.

Full Specs

  Quadro 4000 Radeon R9 A375
Architecture Fermi GCN 1.0
Code name GF100 Venus
Type Workstation Desktop
Release date 2 November 2010 no data
Pipelines 256 640
Core clock speed 475 MHz 900 MHz
Boost Clock 925 MHz
Transistor count 3,100 million 1,500 million
Manufacturing process technology 40 nm 28 nm
Texture fill rate 15.20 37.00
Floating-point performance 486.4 gflops
Length 241 mm
Memory bus width 256 Bit 128 Bit
Memory clock speed 2808 MHz 4.5 GB/s
Memory bandwidth 89.86 GB/s 72 GB/s
DirectX 12 (11_0) 12 (11_1)
Shader Model 5.1 5.1
OpenGL 4.6 4.6
OpenCL 1.1 1.2
Vulkan N/A 1.2
CUDA 2.0
Bitcoin / BTC (SHA256) 44 Mh/s
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