Quadro 4000 vs Radeon R9 M375X

Find out if it is worth upgrading your current GPU setup by comparing Quadro 4000 and Radeon R9 M375X. Here you can take a closer look at graphics cards specs, such as core clock speed, memory type and size, display connectors, etc. The price, overall benchmark and gaming performances are usually defining factors when it comes to choosing between Quadro 4000 and Radeon R9 M375X. Make sure that the graphics card has compatible dimensions and will properly fit in your new or current computer case. Also these graphics cards may have different system power recommendations, so take that into consideration and upgrade your PSU if necessary.

Main Specs

  Quadro 4000 Radeon R9 M375X
Power consumption (TDP) 142 Watt
Interface PCIe 2.0 x16 PCIe 3.0 x16
Supplementary power connectors 1x 6-pin
Memory type GDDR5 GDDR5
Maximum RAM amount 2 GB 4 GB
Display Connectors 1x DVI, 2x DisplayPort No outputs
  Check Price
  • Quadro 4000 is connected by PCIe 2.0 x16, and Radeon R9 M375X uses PCIe 3.0 x16 interface.
  • Radeon R9 M375X has 2 GB more memory, than Quadro 4000.
  • Both cards are used in Desktops.
  • Quadro 4000 is build with Fermi architecture, and Radeon R9 M375X - with GCN 1.0.
  • Core clock speed of Radeon R9 M375X is 450 MHz higher, than Quadro 4000.
  • Quadro 4000 is manufactured by 40 nm process technology, and Radeon R9 M375X - by 28 nm process technology.
  • Memory clock speed of Quadro 4000 is 1683 MHz higher, than Radeon R9 M375X.

Game benchmarks

high / 1080p 6−7 9−10
ultra / 1080p 4−5 5−6
QHD / 1440p 0−1 0−1
low / 720p 16−18 21−24
medium / 1080p 8−9 12−14
The average gaming FPS of Radeon R9 M375X in Assassin's Creed Odyssey is 33% more, than Quadro 4000.

Full Specs

  Quadro 4000 Radeon R9 M375X
Architecture Fermi GCN 1.0
Code name GF100 Tropo
Type Workstation Desktop
Release date 2 November 2010 5 May 2015
Pipelines 256 640
Core clock speed 475 MHz 925 MHz
Boost Clock 1015 MHz
Transistor count 3,100 million 1,500 million
Manufacturing process technology 40 nm 28 nm
Texture fill rate 15.20 40.60
Floating-point performance 486.4 gflops 1,299 gflops
Length 241 mm
Memory bus width 256 Bit 128 Bit
Memory clock speed 2808 MHz 1125 MHz
Memory bandwidth 89.86 GB/s 72 GB/s
DirectX 12 (11_0)
Shader Model 5.1 5.1
OpenGL 4.6 4.4
OpenCL 1.1 Not Listed
Vulkan N/A
CUDA 2.0
FreeSync +
Bus support PCIe 3.0
Bitcoin / BTC (SHA256) 44 Mh/s
Eyefinity +
HD3D +
PowerTune +
DualGraphics +
ZeroCore +
Switchable graphics +
Mantle +
Compute units 10
  Check Price