Quadro 6000 vs Radeon R9 M375X

If you are going to buy a new graphics card and are choosing between Quadro 6000 and Radeon R9 M375X, there are a couple of things to consider. Cards with more VRAM in general perform better and allow you to play on higher graphics settings. Size also makes a difference. A model with a large heatsink can occupy up to three expansion slots on a motherboard. Be sure you have enough room in your PC case. When comparing GPUs with different architectures, more processing cores and even higher TFLOPS will not always translate to better performance. To help you decide which GPU you need, we have measured frame rates in a number of popular games. For more on how the Quadro 6000 stacks up against Radeon R9 M375X, check out specs charts below.

Main Specs

  Quadro 6000 Radeon R9 M375X
Power consumption (TDP) 204 Watt
Interface PCIe 2.0 x16 PCIe 3.0 x16
Supplementary power connectors 1x 6-pin + 1x 8-pin
Memory type GDDR5 GDDR5
Maximum RAM amount 6 GB 4 GB
Display Connectors 1x DVI, 2x DisplayPort, 1x S-Video No outputs
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  • Quadro 6000 is connected by PCIe 2.0 x16, and Radeon R9 M375X uses PCIe 3.0 x16 interface.
  • Quadro 6000 has 2 GB more memory, than Radeon R9 M375X.
  • Both cards are used in Desktops.
  • Quadro 6000 is build with Fermi architecture, and Radeon R9 M375X - with GCN 1.0.
  • Core clock speed of Radeon R9 M375X is 351 MHz higher, than Quadro 6000.
  • Quadro 6000 is manufactured by 40 nm process technology, and Radeon R9 M375X - by 28 nm process technology.
  • Memory clock speed of Quadro 6000 is 1863 MHz higher, than Radeon R9 M375X.

Game benchmarks

high / 1080p 14−16 9−10
ultra / 1080p 8−9 5−6
QHD / 1440p 3−4 0−1
low / 720p 27−30 21−24
medium / 1080p 16−18 12−14
The average gaming FPS of Quadro 6000 in Assassin's Creed Odyssey is 41% more, than Radeon R9 M375X.

Full Specs

  Quadro 6000 Radeon R9 M375X
Architecture Fermi GCN 1.0
Code name GF100 Tropo
Type Workstation Desktop
Release date 10 December 2010 5 May 2015
Pipelines 448 640
Core clock speed 574 MHz 925 MHz
Boost Clock 1015 MHz
Transistor count 3,100 million 1,500 million
Manufacturing process technology 40 nm 28 nm
Texture fill rate 32.14 40.60
Floating-point performance 1,027.7 gflops 1,299 gflops
Length 248 mm
Memory bus width 384 Bit 128 Bit
Memory clock speed 2988 MHz 1125 MHz
Memory bandwidth 143.4 GB/s 72 GB/s
DirectX 12 (11_0)
Shader Model 5.1 5.1
OpenGL 4.6 4.4
OpenCL 1.1 Not Listed
Vulkan N/A
CUDA 2.0
FreeSync +
Bus support PCIe 3.0
Bitcoin / BTC (SHA256) 91 Mh/s
Eyefinity +
HD3D +
PowerTune +
DualGraphics +
ZeroCore +
Switchable graphics +
Mantle +
Compute units 10
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