Quadro K4000 vs Radeon R9 M375X

If you are going to buy a new graphics card and are choosing between Quadro K4000 and Radeon R9 M375X, there are a couple of things to consider. Cards with more VRAM in general perform better and allow you to play on higher graphics settings. Size also makes a difference. A model with a large heatsink can occupy up to three expansion slots on a motherboard. Be sure you have enough room in your PC case. When comparing GPUs with different architectures, more processing cores and even higher TFLOPS will not always translate to better performance. To help you decide which GPU you need, we have measured frame rates in a number of popular games. For more on how the Quadro K4000 stacks up against Radeon R9 M375X, check out specs charts below.

Main Specs

  Quadro K4000 Radeon R9 M375X
Power consumption (TDP) 80 Watt
Interface PCIe 2.0 x16 PCIe 3.0 x16
Supplementary power connectors 1x 6-pin
Memory type GDDR5 GDDR5
Maximum RAM amount 3 GB 4 GB
Display Connectors 1x DVI, 2x DisplayPort No outputs
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  • Quadro K4000 is connected by PCIe 2.0 x16, and Radeon R9 M375X uses PCIe 3.0 x16 interface.
  • Radeon R9 M375X has 1 GB more memory, than Quadro K4000.
  • Both cards are used in Desktops.
  • Quadro K4000 is build with Kepler architecture, and Radeon R9 M375X - with GCN 1.0.
  • Core clock speed of Radeon R9 M375X is 115 MHz higher, than Quadro K4000.
  • Quadro K4000 and Radeon R9 M375X are manufactured by 28 nm process technology.
  • Memory clock speed of Quadro K4000 is 4491 MHz higher, than Radeon R9 M375X.

Game benchmarks

high / 1080p 14−16 9−10
ultra / 1080p 8−9 5−6
QHD / 1440p 3−4 0−1
low / 720p 27−30 21−24
medium / 1080p 16−18 12−14
The average gaming FPS of Quadro K4000 in Assassin's Creed Odyssey is 41% more, than Radeon R9 M375X.

Full Specs

  Quadro K4000 Radeon R9 M375X
Architecture Kepler GCN 1.0
Code name GK106 Tropo
Type Workstation Desktop
Release date 1 March 2013 5 May 2015
Pipelines 768 640
Core clock speed 810 MHz 925 MHz
Boost Clock 1015 MHz
Transistor count 2,540 million 1,500 million
Manufacturing process technology 28 nm 28 nm
Texture fill rate 51.84 40.60
Floating-point performance 1,244 gflops 1,299 gflops
Length 241 mm
Memory bus width 192 Bit 128 Bit
Memory clock speed 5616 MHz 1125 MHz
Memory bandwidth 134.8 GB/s 72 GB/s
DirectX 12 (11_0)
Shader Model 5.1 5.1
OpenGL 4.6 4.4
OpenCL 1.2 Not Listed
Vulkan 1.1.126
CUDA 3.0
Monero / XMR (CryptoNight) 0.21 kh/s
FreeSync +
Bus support PCIe 3.0
Bitcoin / BTC (SHA256) 61 Mh/s
Eyefinity +
HD3D +
PowerTune +
DualGraphics +
ZeroCore +
Switchable graphics +
Mantle +
Compute units 10
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