Quadro 6000 vs Radeon R9 M280X

In this comparison between Quadro 6000 and Radeon R9 M280X you will find out which graphics card performs better in today's games. Bear in mind that third-party versions may have more efficient cooling and higher clock speeds. This will increase cards' performance, though not by much. In addition to raw power you should also take into account the dimensions. Thicker models simply will not fit into a small mini-ITX case. The resolution of your monitor also affects the choice, since 4K gameplay requires a more powerful GPU. And don't overspend on the graphics card. Other parts of your build may also need to be upgraded, save some money for the CPU or power supply. For some people Quadro 6000 will be the best choice, for others Radeon R9 M280X will be their preference. Study the comparison tables below and make your choice.

Radeon R9 M280X is a Laptop Graphics Card

Note: Radeon R9 M280X is only used in laptop graphics. It has lower GPU clock speed compared to the desktop variant, which results in lower power consumption, but also 10-30% lower gaming performance. Check available laptop models with Radeon R9 M280X here:

Main Specs

  Quadro 6000 Radeon R9 M280X
Power consumption (TDP) 204 Watt
Interface PCIe 2.0 x16 PCIe 3.0 x16
Supplementary power connectors 1x 6-pin + 1x 8-pin
Memory type GDDR5 Not Listed
Maximum RAM amount 6 GB
Display Connectors 1x DVI, 2x DisplayPort, 1x S-Video No outputs
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  • Quadro 6000 is connected by PCIe 2.0 x16, and Radeon R9 M280X uses PCIe 3.0 x16 interface.
  • Quadro 6000 is used in Desktops, and Radeon R9 M280X - in Laptops.
  • Quadro 6000 is build with Fermi architecture, and Radeon R9 M280X - with GCN.
  • Core clock speed of Radeon R9 M280X is 326 MHz higher, than Quadro 6000.
  • Quadro 6000 is manufactured by 40 nm process technology, and Radeon R9 M280X - by 28 nm process technology.

Game benchmarks

high / 1080p 14−16 2−3
ultra / 1080p 8−9 1−2
QHD / 1440p 3−4 0−1
low / 720p 27−30 14−16
medium / 1080p 16−18 4−5
The average gaming FPS of Quadro 6000 in Assassin's Creed Odyssey is 240% more, than Radeon R9 M280X.

Full Specs

  Quadro 6000 Radeon R9 M280X
Architecture Fermi GCN
Code name GF100 Saturn XT
Type Workstation Laptop
Release date 10 December 2010 1 February 2015
Pipelines 448 896
Core clock speed 574 MHz 900 MHz
Transistor count 3,100 million 2,080 million
Manufacturing process technology 40 nm 28 nm
Texture fill rate 32.14 61.60
Floating-point performance 1,027.7 gflops 1,792 gflops
Length 248 mm
Memory bus width 384 Bit
Memory clock speed 2988 MHz
Memory bandwidth 143.4 GB/s 96 GB/s
Shared memory -
DirectX 12 (11_0)
Shader Model 5.1 6.3
OpenGL 4.6 4.4
OpenCL 1.1 Not Listed
Vulkan N/A
CUDA 2.0
FreeSync +
Bus support Not Listed
Bitcoin / BTC (SHA256) 91 Mh/s
Laptop size large
HD3D +
PowerTune +
DualGraphics +
ZeroCore +
Switchable graphics +
Mantle +
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