Quadro K4200 vs Radeon R9 M375X

When comparing Quadro K4200 and Radeon R9 M375X, we look primarily at benchmarks and game tests. But it is not only about the numbers. Often you can find third-party models with higher clock speeds, better cooling, or a customizable RGB lighting. Not all of them will have all the features you need. Another thing to consider is the port selection. Most graphics cards have at least one DisplayPort and HDMI interface, but some monitors require DVI. Before you buy, check the TDP of the graphics card - this characteristic will help you estimate the consumption of the graphics card. You may even have to upgrade your PSU to meet its requirements. An important factor when choosing between Quadro K4200 and Radeon R9 M375X is the price. Does the additional cost justify the performance hit? Our comparison should help you make the right decision.

Main Specs

  Quadro K4200 Radeon R9 M375X
Power consumption (TDP) 108 Watt
Interface PCIe 2.0 x16 PCIe 3.0 x16
Supplementary power connectors 1x 6-pin
Memory type GDDR5 GDDR5
Maximum RAM amount 4 GB 4 GB
Display Connectors 1x DVI, 2x DisplayPort No outputs
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  • Quadro K4200 is connected by PCIe 2.0 x16, and Radeon R9 M375X uses PCIe 3.0 x16 interface.
  • Quadro K4200 and Radeon R9 M375X have maximum RAM of 4 GB.
  • Both cards are used in Desktops.
  • Quadro K4200 is build with Kepler architecture, and Radeon R9 M375X - with GCN 1.0.
  • Core clock speed of Radeon R9 M375X is 154 MHz higher, than Quadro K4200.
  • Quadro K4200 and Radeon R9 M375X are manufactured by 28 nm process technology.
  • Memory clock speed of Quadro K4200 is 4275 MHz higher, than Radeon R9 M375X.

Game benchmarks

high / 1080p 21−24 9−10
ultra / 1080p 12−14 5−6
QHD / 1440p 7−8 0−1
4K / 2160p 5−6
low / 720p 40−45 21−24
medium / 1080p 27−30 12−14
The average gaming FPS of Quadro K4200 in Assassin's Creed Odyssey is 116% more, than Radeon R9 M375X.

Full Specs

  Quadro K4200 Radeon R9 M375X
Architecture Kepler GCN 1.0
Code name GK104 Tropo
Type Workstation Desktop
Release date 22 July 2014 5 May 2015
Pipelines 1344 640
Core clock speed 771 MHz 925 MHz
Boost Clock 784 MHz 1015 MHz
Transistor count 3,540 million 1,500 million
Manufacturing process technology 28 nm 28 nm
Texture fill rate 87.81 40.60
Floating-point performance 2,107 gflops 1,299 gflops
Length 241 mm
Memory bus width 256 Bit 128 Bit
Memory clock speed 5400 MHz 1125 MHz
Memory bandwidth 172.8 GB/s 72 GB/s
DirectX 12 (11_0)
Shader Model 5.1 5.1
OpenGL 4.6 4.4
OpenCL 1.2 Not Listed
Vulkan 1.1.126
CUDA 3.0
FreeSync +
Bus support PCIe 3.0
Bitcoin / BTC (SHA256) 119 Mh/s
Eyefinity +
HD3D +
PowerTune +
DualGraphics +
ZeroCore +
Switchable graphics +
Mantle +
Compute units 10
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